There are several opportune moments to thank your subscribers: - Immediately upon subscription: Send a welcome email expressing your gratitude. - After a purchase: Thank them for their trust and provide additional value, such as a discount code for their next purchase. - During special occasions: Show appreciation on their birthdays, anniversaries, or holidays. - Milestones: Thank them for being part of your journey when you reach significant milestones, such as your business anniversary or subscriber milestones.