1. Segmentation: Segmenting your email list allows you to send more personalized and relevant messages to different groups, improving engagement and reducing the risk of being marked as spam. 2. Automation Tools: Utilize email automation tools to streamline the process of sending emails. These tools can schedule and send emails based on user actions or predefined timelines. 3. Throttling: Throttling your email sends can help manage the load on your servers and reduce the risk of being flagged by ISPs. This involves sending emails in batches over a period rather than all at once. 4. Monitoring and Analytics: Keep an eye on your email metrics to understand how your high-volume sends are performing. Use this data to tweak your campaigns for better results.